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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -Heterochromatin Protein p25 (CBX1, Chromobox Protein Homolog 1, HP1Hsbeta, Heterochromatin Protein 1 Homolog beta, HP1 beta, M31, Modifier 1 Protein, p25beta, CBX)

Anti -Heterochromatin Protein p25 (CBX1, Chromobox Protein Homolog 1, HP1Hsbeta,
Heterochromatin Protein 1 Homolog beta, HP1 beta, M31, Modifier 1 Protein, p25beta, CBX)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
CBX1 is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.
Catalog #H2034-51Q
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 1:32,000 & 0.3-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QSQKTAHETDKSE from an internal region of human CBX1.
SpecificityRecognizes human CBX1. Species sequence homology: Canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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