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Abs to Transcription Factors, Homeobox (HOX)
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Anti -Hex (Hematopoietically Expressed Homeobox, HHEX, HMPH, Homeobox Protein HEX, HOX11L-PEN, PRH, PRHX)
Anti -Hex (Hematopoietically Expressed Homeobox, HHEX, HMPH, Homeobox Protein HEX,
HOX11L-PEN, PRH, PRHX)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IP IC FC |
|
| Hex, the hematopoietically-expressed homeobox protein (proline-rich homeodomain protein/PRH) is a transcription factor that is important in the control of cell proliferation and differentiation and in the regulation of multiple processes in embryonic development.Hex contains two domains that can independently bring about transcriptional repression. The Hex homeodomain represses transcription by binding to TATA box sequences, whereas the proline-rich N-terminal domain of Hex can repress transcription when attached to a heterologous DNA-binding domain (1).Hex is expressed in primitive endoderm, in some endoderm-derived tissues and in endothelial and hematopoietic precursors.Expression is extinguished during | | | terminal differentiation of endothelial and hematopoietic cells as well as in adult lung (2). | | | | | | Applications: | | | Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation andImmunocytochemistry. Other applications not tested. | | | Catalog # | H2034-85B | | Recommended Dilution | Flow Cytometry: 1:20 | | Western Blot: 1:1000-1:2000 | | Immunoprecipitation: 1:40 | | Immunocytochemistry: 1:100-1:250 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9H366 | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA. | | Purity | Supernatant | | Immunogen | A synthetic peptide corresponding to residues in human Hex. | | Specificity | Recognizes human Hex. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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