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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -Hex (Hematopoietically Expressed Homeobox, HHEX, HMPH, Homeobox Protein HEX, HOX11L-PEN, PRH, PRHX)

Anti -Hex (Hematopoietically Expressed Homeobox, HHEX, HMPH, Homeobox Protein HEX,
HOX11L-PEN, PRH, PRHX)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IC FC
Hex, the hematopoietically-expressed homeobox protein (proline-rich homeodomain protein/PRH) is a transcription factor that is important in the control of cell proliferation and differentiation and in the regulation of multiple processes in embryonic development.Hex contains two domains that can independently bring about transcriptional repression. The Hex homeodomain represses transcription by binding to TATA box sequences, whereas the proline-rich N-terminal domain of Hex can repress transcription when attached to a heterologous DNA-binding domain (1).Hex is expressed in primitive endoderm, in some endoderm-derived tissues and in endothelial and hematopoietic precursors.Expression is extinguished during
terminal differentiation of endothelial and hematopoietic cells as well as in adult lung (2).
Applications:
Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation andImmunocytochemistry. Other applications not tested.
Catalog #H2034-85B
Recommended DilutionFlow Cytometry: 1:20
Western Blot: 1:1000-1:2000
Immunoprecipitation: 1:40
Immunocytochemistry: 1:100-1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H366
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in human Hex.
SpecificityRecognizes human Hex.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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