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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -HFE (Hereditary Hemochromatosis Protein, HLA-H, HLAH)

Anti -HFE (Hereditary Hemochromatosis Protein, HLA-H, HLAH)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IF
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
Catalog #H2500-04A
ApplicationsSuitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1, k
Clone No1G12
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified.
ImmunogenHFE (NP_000401, 115-206aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human HFE.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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