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You are here:Home » Antibodies » Abs to Histones » Anti -Histone H3, acetylated (Lys56) (H3, H3/A, H3FA, Histone Cluster 1 H3a, HIST1H3A, Histone H3.1, Histone H3.3)

Anti -Histone H3, acetylated (Lys56) (H3, H3/A, H3FA, Histone Cluster 1 H3a, HIST1H3A,
Histone H3.1, Histone H3.3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH IC
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). Acetylation of lysine14 is commonly seen in genes that are being actively transcribed into RNA.
Catalog #H5110-13A6
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-2000
Immunohistochemistry (paraffin): 1:100-250
Immunocytochemistry: 1:100-250
Optimal dilutions to be determined by the researcher.
Positive ControlC6 cell lysates
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9i167
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
PuritySupernatant
ImmunogenSynthetic acetylated peptide corresponding to residues surrounding Lys 56 of Histone H3. Cellular Localization: Nucleus.
SpecificityRecognizes human Histone H3, acetylated on Lys56. Species Crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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