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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -Histone Methyltransferase, SUV39H1 (Histone-lysine N-methyltransferase, SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Full=Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1)

Anti -Histone Methyltransferase, SUV39H1 (Histone-lysine N-methyltransferase, SUV39H1,
Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Full=Position-effect variegation 3-9
homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The histone methyltransferase KMT1A / SUV39H1 is the mammalian homologue of the Drosophila PEV modifier Su(var)3-9 protein. SUV39H1 contains the SET and chromo domains. In eukaryotic cells, SUV39H1 and the methyl-lysine binding protein HP1 interact to repress transcription at heterochromatic sites. SUV39H1 methylates histone H3 on lysine 9, which generates a binding site for HP1 proteins that plays a role in heterochromatin formation and gene silencing.
Catalog #H5205-05C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa 389 of mouse Histone Methyltransferase.
SpecificityRecognizes mouse Histone Methyltransferase. Species crossreactivity: human, rat, drosophilia.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHistone-lysine N-methyltransferase, SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Full=Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1


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