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You are here:Home » Antibodies » Abs to Infectious Disease HIV » Anti -HIV-1 p24 (Human Immunodeficiency Virus Type 1)

Anti -HIV-1 p24 (Human Immunodeficiency Virus Type 1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Structural studies demonstrated two distinct domains (N and C-terminal domains) that have different roles in the virus morphogenesis. Additionally, the level of p24 found in the blood serum is used as an indicator of HIV progression. HIV-1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA.
Catalog #H6003-32G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsOptimal dilution to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C256
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.01% sodium azide
PurityPurified by Protein G affinity chromatography
ImmunogenRecombinant HIV-1 p24 (genotype IIIB).
SpecificityRecognizes HIV-1 p24 antigen.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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