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Anti -HIV-1 p24 (Human Immunodeficiency Virus Type 1) (Biotin)
Anti -HIV-1 p24 (Human Immunodeficiency Virus Type 1) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E |
|
| Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Structural studies demonstrated two distinct domains (N and C-terminal domains) that have different roles in the virus morphogenesis. Additionally, the level of p24 found in the blood serum is used as an indicator of HIV progression. HIV-1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. | | | Catalog # | H6003-32H | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Hybridoma | Sp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice. | | Matched Pair | Capture: H6005-10A | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 12K268 | | Host | Mouse | | Concentration | As reported | | Form | Supplied as a liquid in 0.01M PBS, pH 7.0, 1% gelatin, 0.1% sodium azide. Labeled with Biotin. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Purified recombinant HIV-1 P24 (core protein) | | Specificity | Recognizes HIV-1 P24 (core protein). Does not crossreact with HIV-1 GP41 or HIV-2 GP36. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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