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You are here:Home » Antibodies » Abs to Infectious Disease HIV » Anti -HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (Biotin)

Anti -HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified E B IH IC
HIV-1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Catalog #H6003-34F2
ApplicationsSuitable for use in ELISA, Western Blot, Immunocytochemistry, Immunohistochemistry, Human T-cell Research, Drug Screening and gp120 Capture Assays. Other applications not tested.
Recommended DilutionsELISA: 1:2000
Capture ELISA: 1:500 depending on the capture ligand CD4 concentration and gp120 concentration in the test sample. Typical assays with 100ng of solid phase CD4 will detect at least 10ng/ml gp120.
Western Blot: 1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG
Clone No5i20
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 2.5% BSA, 0.01% sodium azide. Labeled with Biotin.
Purity95%
ImmunogenHIV-1 gp120
SpecificityRecognizes HIV-1 gp120, Strain IIIB. Binds to native and recombinant gp120 (V3 loop specific).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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