Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Antibodies-Infectious Disease HIV » Anti -HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (FITC)

Anti -HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (FITC)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Clone Host Grade Applications
Monoclonal Mouse Highly Purified IH FC IF
HIV is a member of the genus Lentivirus, part of the family of Retroviridae, which use reverse transcriptase to convert the viral RNA genome into double stranded DNA. This is then integrated into the cellís DNA, which is followed by latency or active HIV replication. HIV primarily infects CD4+ T lymphocytes, resulting in their dramatic decline. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. If untreated, this can lead to AIDS (Acquired Immunodeficiency Syndrome). Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Catalog #H6003-34F3
ApplicationsSuitable for use in Dot Blot, FACS, Immunohistochemistry and Direct Immunofluorescence. Other applications not tested.
Recommended DilutionsDirect Immunofluorescence: 1:50
Dot Blot: 1:200
Optimal dilutions to be determined by the researcher.
F/P Ratio3-4
Storage and StabilityStore product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No5i20
FormSupplied as a liquid in 10mM Tris, pH 8.0. No stabilizers or preservatives added. Labeled with fluorescein isothiocyanate (FITC).
Purity95% Purified by gel exclusion chromatography.
ImmunogenHIV-1 gp120
SpecificityRecognizes native and recombinant HIV-1 gp120.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links