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You are here:Home » Antibodies » Abs to Infectious Disease HIV » Anti -HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (FITC)

Anti -HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (FITC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Highly Purified FC IF
HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response
Catalog #H6003-34H3
ApplicationsSuitable for use in Dot Blot, Flow Cytometry, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionDot Blot: 1:100
Immunofluorescence (Direct, cell surface): 1:50
Optimal dilutions to be determined by the researcher.
F/P Ratio2-4
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
ConcentrationAs reported
FormSupplied as a liquid in Tris, pH 8. No stabilizers or preservatives added. labeled with fluorescein isothiocyanate (FITC).
PurityPurified ( 95%) by gel exclusion chromatography.
ImmunogenHIV-1.
SpecificityRecognizes native and recombinant HIV-1 gp120 in Dot Blot assays and stains cell surfaces in direct immunofluorescence assays.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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