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You are here:Home » Antibodies » Abs to Infectious Disease HIV » Anti -HIV-1 gp120 (Human Immunodeficiency Virus-1) (Biotin)

Anti -HIV-1 gp120 (Human Immunodeficiency Virus-1) (Biotin)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Purified E B
HIV is a member of the genus Lentivirus, part of the family of Retroviridae, which use reverse transcriptase to convert the viral RNA genome into double stranded DNA. This is then integrated into the cellís DNA, which is followed by latency or active HIV replication. HIV primarily infects CD4+ T lymphocytes, resulting in their dramatic decline. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. If untreated, this can lead to AIDS (Acquired Immunodeficiency Syndrome).
Catalog #H6003-34M1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
Concentration~4mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin.
PurityPurified
ImmunogenPurified native gp120 from strain IIIB.
SpecificityRecognizes for gp120.Gp120 is an exterior envelope glycoprotein on the surface of the virus particle that binds to CD4 and chemokine receptors on macrophages and T-lymphocytes.This antibody does not crossreact with human T or B cells, human or bovine sera.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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