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You are here:Home » Antibodies » Abs to Infectious Disease HIV » Anti -HIV-1 nef, aa163-173 (Human Immunodeficiency Virus-1)

Anti -HIV-1 nef, aa163-173 (Human Immunodeficiency Virus-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells. The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus. The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells. It is also involved in the endocytosis and degradation of receptor protein of the cell surface such as CD 4 and MH4, important for AIDS virus infection.
Catalog #H6004-15C1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No2F5A
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4. No preservatives added.
PurityPurified
ImmunogenHIV-1 nef (aa163-173)
SpecificityRecognizes native and recombinant nef gene product of HIV-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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