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You are here:Home » Antibodies » Abs to Infectious Disease HIV » Anti -HIV-1 p24 (Human Immunodeficiency Virus-1)

Anti -HIV-1 p24 (Human Immunodeficiency Virus-1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Structural studies demonstrated two distinct domains (N and C-terminal domains) that have different roles in the virus morphogenesis. Additionally, the level of p24 found in the blood serum is used as an indicator of HIV progression. HIV-1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA.
Catalog #H6005-10B
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: Reactivity against HIV-1 >10e5
Myeloma Sp2/0-Ag14
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No3H178
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 40% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified recombinant HIV-1 P24 (core protein)
SpecificityRecognizes human HIV-1 p24 (core protein). No crossreactivity with HIV-1 gp41 and HIV-2 gp36.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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