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You are here:Home » Antibodies » Abs to Enzymes, Acetyltransferase » Anti -HIV-1 Tat Interactive Protein (60kD Tat-interactive Protein, TIP60, cPLA(2)-interacting Protein, cPLA2, ESA1, Histone Acetyltransferase HTATIP, HTATIP, HTATIP1, Histone Acetyltransferase KAT5, Lysine Acetyltransferase 5, KAT5, PLIP, TIP)

Anti -HIV-1 Tat Interactive Protein (60kD Tat-interactive Protein, TIP60,
cPLA(2)-interacting Protein, cPLA2, ESA1, Histone Acetyltransferase HTATIP, HTATIP,
HTATIP1, Histone Acetyltransferase KAT5, Lysine Acetyltransferase 5, KAT5, PLIP, TIP)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
TIP60 is a transcription factor, originally isolated as an HIV-1 TAT-interactive protein, known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyl transferases (HATs). TIP60 is a catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. A co-regulator of transcription factors, TIP60 either promotes or suppresses tumorigenesis. TIP60 is an enzyme that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
Catalog #H6007-30F
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.25-1ug/ml
Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Brain lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa 480-530 of human TIP60.
SpecificityRecognizes TIP60.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=2.3.1.48, K(lysine) Acetyltransferase 5


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