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You are here:Home » Antibodies » Abs to HLA » Anti -HLA Class 1 Antigen B7 (FITC)

Anti -HLA Class 1 Antigen B7 (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C.The HLA B gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.
Catalog #H6098-43A
ApplicationsSuitable for use in Flow Cytometry. Other applications have not been tested.
Recommended DilutionFlow Cytometry: Neat-1:10. Use 10ul to label 1x10e6 cells or 100ul whole blood.
Optimal working dilutions to be determined by researcher.
Recommended Negative ControlsI1904-78R3: IgG1 Murine Negative Control (FITC)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No3H2215
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide. Labeled with FITC.
PurityPurified by Protein G affinity chromatography.
ImmunogenPapain solubilized HLA-B7 antigen
SpecificityRecognizes the human HLA-B7 antigen. Does not crossreact with HLA-B27 or other related antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (ie HLA-B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis. Species Crossreactivity: Cynomolgus monkey
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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