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Anti -HLA Class 1 Antigen ABC (HLA ABC, Major Histocompatibility Complex Class I A + B + C, MHC HLA ABC) (PerCP)
Anti -HLA Class 1 Antigen ABC (HLA ABC, Major Histocompatibility Complex Class I A + B +
C, MHC HLA ABC) (PerCP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| HLA-A, B, and C are ~45kD transmembrane glycoproteins in the major histocompatibility complex I (MHC I) family. They contain three alpha domains in their extracellular regions. HLA molecules are expressed on nearly all nucleated cells in association with the 12kD beta 2-Microglobulin. This complex binds peptides derived from pathogenic cytosolic or extracellular proteins such as viral or microbial proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD8+ cytotoxic T cells. The activated cytotoxic T cell then kills the presenting cell. Mismatched MHC I alleles between a host and a donor lead to transplant rejection. | | | Catalog # | H6098-60D | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Absorption | 482nm and 564nm (max) | | Emission | 675nm (max) | | Storage and Stability | May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. PerCP conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2A | | Clone No | W6/32 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with PerCP. | | Purity | Purified by Protein A/G affinity chromatography. | | Immunogen | Membranes from human tonsillar lymphocytes (not from a recombinant protein). | | Specificity | Recognizes human MHC class I, HLA-A, B, and C. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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