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You are here:Home » Antibodies » Abs to HLA » Anti -HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E, MHC Class I Antigen E, HLA-6.2, HLAE)

Anti -HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E, MHC Class I Antigen E,
HLA-6.2, HLAE)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
Catalog #H6098-68G
ApplicationsSuitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoMEM-E/06
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in TBS, 15mM sodium azide, pH 8.0.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to HLA-E refolded with beta2-microglobulin and peptide.
SpecificityRecognizes native surface-expressed human HLA-E, but not denatured heavy chain of HLA-E. Species sequence homology: Primates
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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