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Anti -HLA-DRA (HLA Class II Histocompatibility Antigen, DR alpha Chain, MHC Class II Antigen DRA, HLA-DRA1) (PerCP)
Anti -HLA-DRA (HLA Class II Histocompatibility Antigen, DR alpha Chain, MHC Class II
Antigen DRA, HLA-DRA1) (PerCP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member, which consists of a 34kD (alpha) subunit and one of several 28kD (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), where it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer. | | | Catalog # | H6098-71E | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Hybridoma | Fusion of a mouse myeloma with B cells obtained from a mouse immunized with HLA-DR expressing RPMI8866 cells. | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing PerCP conjugates will result in a substantial loss of activity. PerCP conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10K57 | | Host | Mouse | | Source | Human | | Concentration | 100 Tests/ml | | Form | Supplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Labeled with Peridinin-chlorophyll-protein complex (PerCP). | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant human HLA-DR expressing RPMI8866 cells (Accession #P01903). | | Specificity | Recognizes human HLA-DR. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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