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You are here:Home » Antibodies » Abs to HLA » Anti -HLA Class 2 Antigen DQ (HLA DQ Class II, HLA-DQ)

Anti -HLA Class 2 Antigen DQ (HLA DQ Class II, HLA-DQ)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC IF
MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35kD) and beta (27-30kD) chains. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Catalog #H6099-89E
ApplicationsSuitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Positive ControlTonsil and lymph node
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone NoHG-38
HostMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenT4-positive CTL
SpecificityRecognizes HLA-DQ. Species Crossreactivity: human and porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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