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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified FC IF

DR monomorphic antigen is expressed on hematopoietic progenitors, B lymphocytes, monocytes/macrophages, dendritic cells, langerhans cells, activated T cells, some endothelial and epithelial cells, but not on resting T lymphocytes, erythrocytes and platelets. HLA-DR antigen is also expressed at high levels on B lymphocyte leukemia cells and cells of CML-LBC, at moderate levels on the cells of AML-M1/M2, M4 and M5, but not or little on the cells of AML-M3 and CML. Anti HLA-DR Ab might be used as valuable reagent in diagnosis and classification of leukemias.
Catalog #	H6099-95J
Applications	Suitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilutions	Flow Cytometry: 0.03ug/100ul peripheral blood using indirect Immunofluorescence staining.
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2b
Clone No	5F62
Host	Mouse
Source	Human
Concentration	As reported
Form	Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Purity	Purified by Protein G affinity chromatography.
Specificity	Recognizes a 28 and 34kD a, b heterodimer glycoprotein named class II major histocompatibility complex (or human leukocyte antigen) DR monomorphic antigen.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.