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You are here:Home » Antibodies » Antibodies-HLA » Anti -HLA Class 2 Antigen DR (HLA-DR)

Anti -HLA Class 2 Antigen DR (HLA-DR)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH FC
This antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kD a (heavy) chain and a 27kD B (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. This antibody has been reported to block mixed lymphocyte reactions.
Catalog #H6100-42L
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 0.5ug/10e6 cells in 100ul
Immunohistochemistry: Acetone-fixed, frozen sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
Clone TypeMonoclonal
Clone NoL243
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenHuman HLA-DR.
SpecificityRecognizes human HLA-DR. Species Crossreactivity: chimpanzee, baboon, Cynomolgus, Rhesus, Marmoset, Cotton-topped Tamarin, Squirrel Monkey, African Green, Pigtailed Macaque and canine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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