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You are here:Home » Antibodies » Abs to HLA » Anti -HLA Class 2 Antigen DR (HLA-DR)

Anti -HLA Class 2 Antigen DR (HLA-DR)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
This monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kD a (heavy) chain and a 27kD B (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
Catalog #H6100-42Q
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 0.5ug/10e6 cells in 100ul
Immunohistochemistry: Frozen
Immunohistochemistry: Formalin fixed paraffin embedded
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b, k
Clone NoLN3
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman PBL.
SpecificityRecognizes human HLA-DR. Species Crossreactivity: rhesus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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