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You are here:Home » Antibodies » Abs to Coenzyme A » Anti -HMG-CoA Reductase (Hydroxymethylglutaryl-CoA reductase)

Anti -HMG-CoA Reductase (Hydroxymethylglutaryl-CoA reductase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
HMG-CoA reductase (HMGCR) is the rate-limiting enzyme for cholesterol biosynthesis. HMGCR is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from the product of the reductase reaction. Statin, a class of cholesterol-lowering drugs inhibits HMGCR by lowering plasma cholesterol.
Catalog #H6201-01C
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide surrounding aa830 of human HMG-CoA Reductase
SpecificityRecognizes human HMG-CoA Reductase.
Species CrossreactivityMouse and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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