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You are here:Home » Antibodies » Abs to Homeobox (HOX) » Anti -HOXA9 (Homeobox Protein Hox-A9, Homeobox Protein Hox-1G, HOX1G)

Anti -HOXA9 (Homeobox Protein Hox-A9, Homeobox Protein Hox-1G, HOX1G)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes like cell identity, cell division and differentiation. The HOXA9 gene encodes a class I homeodomain protein which is involved in hematopoesis and myeloid differentiation. It shows different splice variants like a 1.8-kb homeobox-containing transcript in fetal brain, lung, liver, and kidney, and 2.2- and 3.3-kb transcripts in fetal and adult kidney and in adult skeletal muscle. Fusion between the HOXA9 gene and the nucleoporin gene NUP98, a member of the GLFG nucleoporin family, on 11p15 occurs as a consequence of leukemia-associated chromosomal translocations. So NUP98-HOXA9 is associated with the t(7;11)(p15;p15) translocation in acute myeloid leukemia, myelodysplastic syndrome, and blastic crisis of chronic myeloid leukemia.
Catalog #H7022-90
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlKidney
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa225-272 of human HOXA9.
SpecificityRecognizes human Homeobox protein A9/HOXA9. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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