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You are here:Home » Antibodies » Abs to Homeobox (HOX) » Anti -Homeobox D10 (HOXD10, HOX4, HOX4D, HOX4E, Hox-4.4, Homeo box 4D, Homeo box D10)

Anti -Homeobox D10 (HOXD10, HOX4, HOX4D, HOX4E, Hox-4.4, Homeo box 4D, Homeo box D10)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Catalog #H7024-23
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32000
Western Blot: 0.2-0.6ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Kidney lysates
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide with sequence PNRSCRIEQPVTQQ, from the internal region of human HOXD10 (NP_002139.2).
SpecificityRecognizes human HOXD10 at ~37kD. Species sequence homology: mouse, rat, equine, bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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