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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -HSC70 Interacting Protein (HIP, AAG2, Aging Associated Protein 2, FAM10A1, FLJ27260, HSPABP1, MGC129952, OTTHUMP00000028873, PRO0786, Progesterone Receptor Associated p48 Protein, Putative Tumor Suppressor ST13, Renal Carcinoma Antigen NY REN 33, SNC6, Su

Anti -HSC70 Interacting Protein (HIP, AAG2, Aging Associated Protein 2, FAM10A1, FLJ27260,
HSPABP1, MGC129952, OTTHUMP00000028873, PRO0786, Progesterone Receptor Associated p48
Protein, Putative Tumor Suppressor ST13, Renal Carcinoma Antigen NY REN 33, SNC6, Su

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH FC
ST13/HIP is a cytoplasmic co-chaperone involved in the regulation of Hsc70 chaperone activity and the maturation of progesterone receptor. ST13/HIP is made of two structural and functional domains, an NH2-terminal domain, responsible for the dimerization and the overall asymmetry of the molecule, and a COOH-terminal globular domain, both involved in Hsc70 and unfolded protein binding (1). By collaborating with other positive co-factors such as Hsp40 and the Hsp70-Hsp90 organizing protein (Hop), or competing with negative co-factors such as Bcl2-associated athanogen 1 (Bag1), ST13/HIP facilitates may facilitate the chaperone function of Hsc/Hsp70 in protein folding and repair, and in controlling the activity of regulatory proteins
such as steroid receptors and regulators of proliferation or apoptosis (2).
Applications:
Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested.
Catalog #H7651-07A
Recommended DilutionFlow Cytometry: 1:150
Western Blot: 1:10,000-1:50,000
Immunohistochemistry: 1:100-1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H393
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in human ST13/HIP.
SpecificityRecognizes human ST13/HIP. Species Crossreactivity: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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