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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -HSPE1 (Heat Shock 10kDa Protein 1, 10kD Heat Shock Protein Mitochondrial, Hsp10, 10kD Chaperonin, Chaperonin 10, CPN10, Early Pregnancy Factor, EPF, GROES)

Anti -HSPE1 (Heat Shock 10kDa Protein 1, 10kD Heat Shock Protein Mitochondrial, Hsp10,
10kD Chaperonin, Chaperonin 10, CPN10, Early Pregnancy Factor, EPF, GROES)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP IH
Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s). Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides.
Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process (1). Cpn10 has been located in human platelets, but is also present in human maternal serum (2, 3). It has been reported that human Cpn10 is
identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy (4).
Catalog #H7656-41
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot:1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS with 0.02% sodium azide, pH7.3.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman Cpn10 peptide AA 91-101.
SpecificityRecognizes human Cpn10. Species Crossreactivity: mouse, rat, bovine, canine, guinea pig, porcine, sheep, xenopus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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