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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Huntingtin Protein (Huntington Disease)

Anti -Huntingtin Protein (Huntington Disease)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP IH IC
Huntington's disease (HD) is a neurodegenerative disorder caused by an expanding polyglutamine repeat in the huntingtin gene. HD is a mid-life onset autosomal dominant neurodegeneative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years.
Catalog #H7965-02
ApplicationsSuitable for use in ELISA, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:500-1:5000
Immunohistochemistry: 1:500-1:5000. Frozen and microwave oven treated paraffin sections (human from previous lot)
Immunocytochemistry: 1:500-1:5000 using transfected cells
Immunoprecipitation: 1:500-1:5000
Western Blot: 1:1000. Detects huningtin protein on 10ug of rat brain lysates.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No2Q75
HostMouse
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2. No preservative added.
PurityPurified by affinity chromatography.
ImmunogenHuntingtin fragment from aa181-810 as a fusion protein. Species sequence homology: human, monkey, mouse and hamster.
SpecificityRecognizes rat Huntingtin Protein. No detectable crossreactivity to other proteins by Western Blot.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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