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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -HRAS (HRAS1, H-Ras-1, c-H-ras, C-Ha-Ras1, Ha-Ras, GTPase HRas, C-Bas/Has, CTLO, HAMSV, H-RASIDX, K-Ras, p21ras, RASH1, Transforming Protein p21)

Anti -HRAS (HRAS1, H-Ras-1, c-H-ras, C-Ha-Ras1, Ha-Ras, GTPase HRas, C-Bas/Has, CTLO,
HAMSV, H-RASIDX, K-Ras, p21ras, RASH1, Transforming Protein p21)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in the HRAS gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.
Catalog #H8010
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the Center region of human HRAS (KLH).
SpecificityRecognizes human HRAS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesv-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog, N-RAS


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