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You are here:Home » Antibodies » Antibodies-Nucleotides » Anti -8-Hydroxyguanosine (8-OHG)

Anti -8-Hydroxyguanosine (8-OHG)


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Clone Host Grade Applications
Polyclonal Goat Serum E IH
8-hydroxyguanosine (8-OG) is a modified base which occurs in DNA as a result of oxidative stress. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8-OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke.
Catalog #H9076-02
ApplicationsSuitable for use in Immunohistochemistry and ELISA. Other application not tested.
Recommended DilutionsImmunohistochemistry (Paraffin): 1:200
ELISA: 1:100,000-1:250,000
Optimal working dilutions to be determined by researcher.
Recommended Secondary AntibodiesI1904-28C: IgG, H&L (HRP) Pab DkxGt
I1904-28G: IgG, H&L (HRP) (X-Adsorbed) Pab DkxGt
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
ConcentrationNot Determined
FormSupplied as a liquid, 0.1% sodium azide.
SpecificityRecognizes 8-hydroxyguanosine (8-OG) and 8-Hydroxy-2'-deoxyguanosine (8-OHdG). Does not crossreact with other naturally occurring nucleotides.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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