USBio Logo
Subscribe to our newsletter!

REGISTER | SIGN IN

Welcome | LOG OUT

H9100 Mouse Anti-3-Hydroxykynurenine (3-OHKYN)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1,k
Clone Number
P3UI
Grade
Affinity Purified
Applications
E IC IF IHC WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

3-hydroxykynurenine, a chromophore metabolite of tryptophan, acts as UV protectant and an antioxidant in vertebrate lens. This compound reacts with proteins to induce cross-linking and chromophore adducts.

Applications
Suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot, Other applications not tested.
Recommended Dilution
Immunocytochemistry/Immunofluorescence: 1:100-1:200 Western Blot: 2ug/ml. Band at ~66kD observed for 3-OHKYN-modifed BSA. Immunohistochemistry: paraffin Optimal dilutions to be determined by the researcher.
Cellular Localization
Cytoplasmic
Positive Control
3-OHKYN modified BSA
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
3-OHKYN modified KLH
Form
Supplied as a liquidin Tris-glycine, 150mM sodium chloride, 0.05% sodium azide
Purity
Purified by Protein G affinity chromatography
Specificity
Specific for 3-hydroxykynurenine modifications on N-alpha-acetyl lysine, N-alpha-acetyl histidine, N-alpha-acetyl arginine, and N-alpha-acetyl cysteine. It does not recognize the transaminase enzyme involved in the degradation of tryptophan. Reacts with 3-OHKYN modifications in human proteins.
References
Staniszewska, MM and Nagaraj, RH. 3-hydroxykynuenine-mediated modification of human lens proteins. JBC. 280 (23): 22154-22164, 2005
USBio References
No references available
Conjugates
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
Special Offers
30% OFF New Lab Discount Setting up a New Lab?
Apply for our New Lab Discount!
*Receive a 30% off LIST price coupon code via email.
Society Member Discount Members of the GSA, FASEB, ACS and SFN get even bigger discounts!
  • Earn Research Credit Try any antibody for an unspecified use. We'll reward you for your efforts!
    *Receive a 25% off list price coupon code.
    • Contact Us

    Visit our technical library or contact our support staff to answer your questions.

    Telephone:
    1-800-520-3011

    Library | Contact

    Site Map

    ANTIBODIES

    BIOCHEMICALS

    BIOLOGICALS

    CULTURE MEDIA

    MOLECULAR BIOLOGY

    KITS AND ASSAYS

    Technical Resources

    BIO DICTIONARY

    CITEAB

    ENTREZ GENE

    GENBANK

    HISTOLOGY GUIDE

    NCBI

    OMIM

    PROTEIN RESOURCES

    PROTOCOLS

    PUBMED

    UNIPROT

    Distributors

    For customers outside of the United States, please use one of our many distributors.

    View Distributors

    Payment Methods

    We accept the following payment methods as well as pay-by-invoice.

    MasterCard Visa PayPal
    © 2023-2024 United States Biological - All Rights Reserved