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You are here:Home » Antibodies » Abs to Hypoxia » Anti -Hypoxia Inducible Factor 3a (Hypoxia Inducible Factor 3 alpha, Hypoxia Inducible Factor 3 alpha Subunit, Hypoxia Inducible Factor Three alpha, HIF-3a, HIF3A, HIF3 alpha, HIF-3A4, Inhibitory PAS Domain Protein, IPAS, MOP7, PASD7)

Anti -Hypoxia Inducible Factor 3a (Hypoxia Inducible Factor 3 alpha, Hypoxia Inducible
Factor 3 alpha Subunit, Hypoxia Inducible Factor Three alpha, HIF-3a, HIF3A, HIF3 alpha,
HIF-3A4, Inhibitory PAS Domain Protein, IPAS, MOP7, PASD7)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.
Catalog #H9810-05C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Positive Control Reticulocyte lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormTris-citrate/phosphate buffer, pH 7-8
PurityPurified by immunoaffinity chromatography.
ImmunogenBacterially expressed human HIF-3 alpha (N-terminus).
SpecificityRecognizes mouse HIF-3 alpha.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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