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You are here:Home » Antibodies » Abs to Ligands » Anti -ICOS Ligand (CD275, Inducible T cell Co-stimulator Ligand, B7-H2, B7 Homolog 2, B7-like Protein GL50, B7 Related Protein 1, B7H2, B7RP-1, B7RP1, GL50, ICOS LG, ICOSLG, KIAA0653, LICOS, Transmembrane Protein B7-H2 ICOS Ligand)

Anti -ICOS Ligand (CD275, Inducible T cell Co-stimulator Ligand, B7-H2, B7 Homolog 2,
B7-like Protein GL50, B7 Related Protein 1, B7H2, B7RP-1, B7RP1, GL50, ICOS LG, ICOSLG,
KIAA0653, LICOS, Transmembrane Protein B7-H2 ICOS Ligand)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH FC
CD275, also known as ICOS ligand, is a member of the B7 family, and interaction with its receptor CD278 (ICOS) plays an important role in T cell co-stimulation and inflammatory immune reactions.
Catalog #I0650-01K1
CD275 is expressed on activated B-cells, monocytes and dendritic cells and is also induced on non-lymphoid tissue cells such as endothelial cells, epithelial cells and muscle cells. CD275 has an important physiological role in the reactivation of effector/memory T cells on the endothelium, thus controlling entry of immune cells into inflamed tissue.
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:20-1:200; 10ul labels 10e6 cells in 100ul
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.
HybridomaP3U1 myeloma cells with spleen cells from BALB/c mice.
Positive Control TissueTonsil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9A192
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
PurityPurified by Protein G affinity chromatography
ImmunogenCD275-L cells
SpecificityRecognizes human ICOS ligand.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB7RP-1, B7h, LICOS, GL50


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