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You are here:Home » Antibodies » Abs to Ligands » Anti -ICOSLG (ICOS Ligand, B7 Homolog 2, B7-H2, B7-like Protein Gl50, B7-related Protein 1, B7RP-1, CD275, B7H2, B7RP1, ICOSL, KIAA0653)

Anti -ICOSLG (ICOS Ligand, B7 Homolog 2, B7-H2, B7-like Protein Gl50, B7-related Protein
1, B7RP-1, CD275, B7H2, B7RP1, ICOSL, KIAA0653)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IP IH FC
B7-H2 is detected on the surface of monocyte derived immature dendritic cells. It is a putative ligand for ICOS (inducible costimulator) from CD28 family of T cell-costimulators. Costimulatory interactions between the B7 family ligands and their receptors like CD28, CTLA-4 and ICOS play critical role in the growth, differentiation and death of T cells. B7-H2 has four conserved structural cysteins in its extracellular domain which are believed to form the Ig V like and IgC-like domain. In addition, B7-H2 has a conserved tyrosine residue in the Ig V-like domain at position of aa80. B7-H2 shares ~46% homology at aa level to B7h/B7RP-1, a recently described B7 like protein of mouse origin.
Catalog #I0650-04A
ApplicationsSuitable for use in Flow Cytometry, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No2D3
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human ICOSLG.
SpecificityRecognizes human ICOSLG.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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