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Abs to Protein Kinase Inhibitors
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Anti -IkB beta (IkappaB beta, IKBB, NFkB Inhibitor beta, NF kappa BIB, NFkBIB, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B cells Inhibitor beta, Thyroid Receptor Interacting Protein 9, TR Interacting Protein 9, TRIP9)
Anti -IkB beta (IkappaB beta, IKBB, NFkB Inhibitor beta, NF kappa BIB, NFkBIB, Nuclear
Factor of kappa Light Polypeptide Gene Enhancer in B cells Inhibitor beta, Thyroid
Receptor Interacting Protein 9, TR Interacting Protein 9, TRIP9)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| NFkB exists in the cytoplasm as a complex with a 38kDa inhibitor protein, IkB (MAD-3). Activation of NFkB by different stimuli, including TNFa and PMA, requires the dissociation of the inhibitor protein. Dissociation is regulated by the phosphorylation of IkB on serine residues 32 and 36 which targets IkB for ubiquinitation and proteasome mediated degradation. The NFkB complex then translocates to the nucleus and activates transcription of responsive genes. | | | Catalog # | I2500-09C | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot:1:500-1:1,000 | | Immunohistochemistry:1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic non-phosphopeptide corresponding to human IkB-beta around the phosphorylation site of serine 23 (L-G-SP-L-G). | | Specificity | Recognizes human IkB-beta. Species Cross-Reactivity: mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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