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IKK epsilon, Kinase Inhibitor II
IKK epsilon, Kinase Inhibitor II
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| A benzimidazole analog that acts as a potent and selective inhibitor of IKK-epsilon kinase (IC50=40nM); displays >125-fold selectivity over IKK-alpha and IKK-beta. | | | Catalog # | I3000-60E | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Protect from air and light. | | CAS Number | 862812-98-4 | | Molecular Formula | C H N O S | | Molecular Weight | 469.53 | | Purity | ~97% (HPLC) | | Form | Supplied as a crystalline solid. Reconstitute with DMSO. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 5-(5, 6- dimethoxy- 1H- benzimidazol- 1- yl)- 3- [[2- (methylsulfonyl)phenyl]methoxy]- 2- thiophenecarbonitrile |
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