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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -ICAM5 (Intercellular Adhesion Molecule 5, ICAM-5, Telencephalin, TLCN, TLN)

Anti -ICAM5 (Intercellular Adhesion Molecule 5, ICAM-5, Telencephalin, TLCN, TLN)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E IH
ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Catalog #I5004-05A
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Immunohistochemistry (Paraffin): 2-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-ESPAEGEVFAIQ, from human ICAM5, at C-terminal (NP_003250.3).
SpecificityRecognizes human ICAM5. Species sequence homology: Bovine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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