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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (APC)

Anti -Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
IGSF3 (Immunoglobulin superfamily member 3; also known as EWI-3) is a member of the EWI subfamily of the Ig- superfamily of molecules. It is a type I transmembrane protein that likely exists as a homodimer in kidney and lung. The mature molecule is 1195aa in length, and contains an extended 1127aa extracellular domain (ECD; aa20-1146). There are seven ECD V-type Ig-like domains, the second of which exhibits a characteristic Glu-Trp-Ile motif. There are at least two potential splice variants. One shows a truncation after Pro833; a second shows a deletion of aa408-427. Over aa20-1125, human IGSF3 shares 92% aa identity with mouse IGSF3.
Catalog #I7502-95A
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul labels 1-2.5 x 10e5 cells
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells from a mouse immunized with purified, NS0-derived human IGSF3 (aa20-1125).
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of enzymatic activity. APC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L833
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in saline, 0.1% sodium azide, 0.5% BSA. Labeled with APC.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived, recombinant human IGSF3 (aa20-1125; Accession # NP_001533).
SpecificityRecognizes human IGSF3. Species Crossreactivity: mouse (92%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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