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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (PE)

Anti -Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
IGSF3 (Immunoglobulin superfamily member 3; also known as EWI-3) is a member of the EWI subfamily of the Ig- superfamily of molecules. It is a type I transmembrane protein that likely exists as a homodimer in kidney and lung. The mature molecule is 1195aa in length, and contains an extended 1127aa extracellular domain (ECD; aa20-1146). There are seven ECD V-type Ig-like domains, the second of which exhibits a characteristic Glu-Trp-Ile motif. There are at least two potential splice variants. One shows a truncation after Pro833; a second shows a deletion of aa408-427. Over aa20-1125, human IGSF3 shares 92% aa identity with mouse IGSF3.
Catalog #I7502-95B
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul labels 1-2.5 x 10e5 cells
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells from a mouse immunized with purified, NS0-derived human IGSF3 (aa20-1125).
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L834
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived, recombinant human IGSF3 (aa20-1125; Accession #
NP_001533).
SpecificityRecognizes human IGSF3. Species Crossreactivity: mouse (92%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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