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Anti -Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (PE)
Anti -Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (PE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| IGSF3 (Immunoglobulin superfamily member 3; also known as EWI-3) is a member of the EWI subfamily of the Ig- superfamily of molecules. It is a type I transmembrane protein that likely exists as a homodimer in kidney and lung. The mature molecule is 1195aa in length, and contains an extended 1127aa extracellular domain (ECD; aa20-1146). There are seven ECD V-type Ig-like domains, the second of which exhibits a characteristic Glu-Trp-Ile motif. There are at least two potential splice variants. One shows a truncation after Pro833; a second shows a deletion of aa408-427. Over aa20-1125, human IGSF3 shares 92% aa identity with mouse IGSF3. | | | Catalog # | I7502-95B | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 10ul labels 1-2.5 x 10e5 cells | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Mouse myeloma cells with B cells from a mouse immunized with purified, NS0-derived human IGSF3 (aa20-1125). | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9L834 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE). | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | NS0-derived, recombinant human IGSF3 (aa20-1125; Accession # | | NP_001533). | | Specificity | Recognizes human IGSF3. Species Crossreactivity: mouse (92%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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