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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -Importin 11 (importin-11, imp11, Ran-binding Protein 11, RanBP11)

Anti -Importin 11 (importin-11, imp11, Ran-binding Protein 11, RanBP11)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Principal Names: Importin-11 (IPO11); Imp11; Ran-binding protein 11 (RanBP11); Official Gene Symbol: IPO11 Gene ID: 51194 (Human) Gene Map Locus: 5q12.1 (Human) Importin-11 is a novel member of Karyopherin family. Karyopherins are transport receptors that mediate the transport of protein and RNA across the nucleus and cytoplasm. Importin-11 consists of an N-terminal Ran-binding domain, a central cargo-binding region and C-terminal region. It interacts with Ran-GTPase and constitutively shuttles between the nucleus and cytoplasm. Reports suggest Importin-11 primarily mediates the transport of ribosomal protein L12 and UbcM2, an E2 ubiquitin-conjugating enzyme.
Catalog #I7510-10
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Positive Control HeLa lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormPBS containing 0.2% gelatin
PurityPurified by immunoaffinity chromatography.
ImmunogenA portion of amino acids 1-50 of human Importin-11 was used as the immunogen.
SpecificityThe amino acid sequence used as immunogen is 100% homologous in human, rhesus monkey, chimp, bovine, canine, mouse and rat, and 94% homologous in xenopus. Species Crossreactivity: Bovine, Chimpanzee, canine, Human, Mouse, Rat, Rhesus Monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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