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You are here:Home » Antibodies » Abs to Infectious Disease Influenza » Anti -Influenza A Nucleoprotein (NP)

Anti -Influenza A Nucleoprotein (NP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56.
Catalog #I7650-81J
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from BALB/c mice.
SourceAscites
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG3
Clone No8J92
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein A chromatography. >90% pure (SDS-PAGE).
ImmunogenPurified Influenza A/New Caledonia/20/99 (H1N1)
SpecificityRecognizes Nucleoprotein (NP) of Influenza A. Does not crossreact with nucleoprotein of Influenza B virus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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