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You are here:Home » Antibodies » Abs to Infectious Disease Influenza » Anti -Influenza A, Nucleoprotein (NP)

Anti -Influenza A, Nucleoprotein (NP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IC
The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1.
NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56 (Portela et al 2002).
Catalog #I7650-83E
ApplicationsSuitable for use in ELISA and Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8L387
HostMouse
ConcentrationAs reported
FormPBS with 0.1% sodium azide, pH 7.4
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified influenza virus type A strain H1N1.
SpecificityThis antibody reacts with nucleoprotein (NP), which is common for Influenza A(H1N1), A(H3N2) and other Influenza A viruses. Species Crossreactivity: Reacts with all serotypes of of influenza virus A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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