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You are here:Home » Antibodies » Abs to Infectious Disease Influenza » Anti -Influenza A, Matrix 2 Protein (M2)

Anti -Influenza A, Matrix 2 Protein (M2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IC IF
Influenza A virus is an enveloped virus encoding 10 polypeptides. RNA segment 7 encodes for two proteins: M1 (matrix 1) and M2 (matrix 2). M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA. M2 protein is a transmembrane protein composed of three Domains: 1) 24 residues representing the N-terminal region, 2) 19 hydro-phobic residues that serve as a membrane anchor, and 3) 54 residues near the C-terminal in the cytoplasmic domain. The M2 protein has been found to play a role in Influenza replication and assembly of virion particles. Further experimentation has demonstrated that this protein is an acid-activated ion channel for virus replication.
Catalog #I7650-83H
ApplicationsSuitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8L388
HostMouse
Concentration~1mg/ml
FormPBS, 1mg/ml BSA
PurityPurified by immunoaffinity chromatography.
ImmunogenThe M2 protein from A/WSN/33-infected CV1 cell lysate. Epitope: Detects the N-terminal of the Influenza A Virus M2 Protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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