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You are here:Home » Antibodies » Abs to Tumor Suppressors » Anti -ING2 (Inhibitor of Growth Protein 2, Inhibitor of Growth 1-like Protein, ING1Lp, p32, p33ING2, ING1L)

Anti -ING2 (Inhibitor of Growth Protein 2, Inhibitor of Growth 1-like Protein, ING1Lp,
p32, p33ING2, ING1L)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
Catalog #I7652-55B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1000
Western Blot: 1-3ug/ml, hepatocarcinoma HEPG2 lysates observed on ~30kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DKSTEKTKKDRRSR, from human ING2, at C-terminal (NP_001555.1).
SpecificityRecognizes human ING2. Species sequence homology: Bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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