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You are here:Home » Antibodies » Abs to Insulin » Anti -Insulin

Anti -Insulin

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B-cell origin such as insulinoma.
Catalog #I7656-06
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Recommended PairSuitable for use as the capture or solid phase antibody.
Matched to I7656-07 as the detection or conjugate (label) antibody.
Affinity Constant7.5 x 10e9 M-1
HybridomaX63-Ag8653 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No1.B.105
HostMouse
SourceHuman
Concentration~5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide. No glycerol added.
PurityPurified by Protein A affinity chromatography (>90%, SDS-PAGE).
ImmunogenPurified human insulin.
SpecificityRecognizes human Insulin. Does not crossreact wtih free C-peptide. Species Crossreactivity: human proinsulin, bovine insulin (30%) and porcine insulin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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