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You are here:Home » Molecular Biology » MB-Growth Factors-IGF » Insulin-Like Growth Factor I, Recombinant, Human (IGF1)

Insulin-Like Growth Factor I, Recombinant, Human (IGF1)


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The Insulin-like growth factor-1 (IGF-1) is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF-1 is predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGF-1 belongs to the insulin gene family, which also contains insulin and relaxin. The IGF-1 is similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. This recombinant human IGF-I is globular protein containing 71 amino acids, and 3 intra-molecular disulfide bonds. Recombinant IGF-1 was expressed in E. coli.
AA Sequence:
Catalog #I7661-09J
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, Aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight7.7kD
SourceRecombinant, Human, (E. coli)
Purity95% by SDS-PAGE. Purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
FormSupplied as a liquid in PBS, pH 7.4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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