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You are here:Home » Molecular Biology » Growth Factors-IGF » Insulin-Like Growth Factor II, Recombinant, Human (Human IGF-II, IGF-II, IGFII, IGFII, IGF2, IGF-2, IGF 2)

Insulin-Like Growth Factor II, Recombinant, Human (Human IGF-II, IGF-II, IGFII, IGFII,
IGF2, IGF-2, IGF 2)

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Specifications

IGF is a well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on Somatotropin. It is believed to be mainly active in adults in contrast to Insulin like Growth Factor 2, which is a major fetal growth factor.
Catalog #I7661-12N
Endotoxin <0.01ng/ug or <0.1EU/ug as per LAL
Biological Activity Recombinant Human Insulin Like Growth Factor-II is fully biologically active when compared to standards. The ED50, calculated by the competitive binding of IGF-II plasma derived to human placental membrane is less then 1.0ng/ml, corresponding to a specific activity of 106IU/mg.
AA SequenceAYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight7.6kD
SourceRecombinant, human, E. coli
Purity97% as determined by RP-HPLC.Reducing and non-reducing SDS-PAGE.
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHuman IGF-II, IGF-II, IGFII, IGFII, IGF2, IGF-2, IGF 2, h-IGF-II, rh-IGF-II, recombinant human IGF-II, recombinant IGF-II, IGF


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