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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin, alphaE (CD103, Human Mucosal Lymphocyte Antigen 1)

Anti -Integrin, alphaE (CD103, Human Mucosal Lymphocyte Antigen 1)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified E B
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin undergoes post-translational cleavage in the extracellular domain that yields disulfide-linked heavy and light chains, In combination with beta 7 (ITGB7) these chains form the E-cadherin binding integrin known as human mucosal lymphocyte-1' antigen (HML-1). This integrin is preferentially expressed on human intestinal intraepithelial lymphocytes (IEL), and in addition to adhesion, it may serve as an accessory molecule for IEL activation.
Catalog #I7661-30H
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa773-817
SpecificityRecognizes human Integrin, alphaE.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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