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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin alpha-1 (CD49a, CD49 Antigen-like Family Member A, Laminin and Collagen Receptor, VLA-1, ITGA1)

Anti -Integrin alpha-1 (CD49a, CD49 Antigen-like Family Member A, Laminin and Collagen
Receptor, VLA-1, ITGA1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
CD49a is a 200kD type I transmembrane glycoprotein, also known as a1 integrin, VLA-1 a chain, or Integrin a1. It associates with CD29 (B1 integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor and that is expressed on activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells.CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration and T cell proliferation and cytokine production.
Catalog #I7661-31S
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 0.5ug/10e5 cells in 100ul
Immunohistochemistry: Acetone-fixed, frozen
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1, k
Clone NoTS2/7
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman CTL line
SpecificityRecognizes human CD49a.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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