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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin alpha2, beta1 (Collagen Receptor, VLA2)

Anti -Integrin alpha2, beta1 (Collagen Receptor, VLA2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH FC
The epitope is dependent on the presence of the (I) domain of alpha 2 integrin subunit and does not bind VLA-2 variant which lacks the Idomain. Inhibits VLA-2 mediated cell adhesion to collagen and laminin. Does not detect alpha 2 integrin subunit by Western blot presumably due to conformational properties of the epitope involved.
Catalog #I7661-32C
ApplicationsSuitable for use in Immunoprecipitation, Flow Cytometry, Inhibition and Immunohistochemistry. Not suitable for Western Blot. Other applications have not been tested.
Recommended DilutionImmunoprecipitation: 2-5ug for lysate of 10e6 cells
Flow Cytometry: 10ug/ml
Immunohistochemistry (frozen tissue sections): 5ug/ml
Inhibition: 10ug/ml Inhibits VLA-2 mediated cell adhesion to collagen and laminin.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No2Q1003
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenIntegrin alpha 2, beta 1
SpecificityRecognizes the human collagen receptor VLA-2 (alpha 2 beta 1) integrin complex. Species Crossreactivity: porcine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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