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Anti -Integrin alpha2, beta1 (Collagen Receptor, VLA2)
Anti -Integrin alpha2, beta1 (Collagen Receptor, VLA2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IP IH FC |
|
| The epitope is dependent on the presence of the (I) domain of alpha 2 integrin subunit and does not bind VLA-2 variant which lacks the Idomain. Inhibits VLA-2 mediated cell adhesion to collagen and laminin. Does not detect alpha 2 integrin subunit by Western blot presumably due to conformational properties of the epitope involved. | | | Catalog # | I7661-32C | | Applications | Suitable for use in Immunoprecipitation, Flow Cytometry, Inhibition and Immunohistochemistry. Not suitable for Western Blot. Other applications have not been tested. | | Recommended Dilution | Immunoprecipitation: 2-5ug for lysate of 10e6 cells | | Flow Cytometry: 10ug/ml | | Immunohistochemistry (frozen tissue sections): 5ug/ml | | Inhibition: 10ug/ml Inhibits VLA-2 mediated cell adhesion to collagen and laminin. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 2Q1003 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Integrin alpha 2, beta 1 | | Specificity | Recognizes the human collagen receptor VLA-2 (alpha 2 beta 1) integrin complex. Species Crossreactivity: porcine | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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